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Article

Functional role of bone morphogenetic protein-4 in isolated canine parietal cells.

American journal of physiology. Gastrointestinal and liver physiology - 1 Sept 2007

Nitsche Hildegard, Ramamoorthy Saravanan, Sareban Mahdi, Pausawasdi Nonthalee, Todisco Andrea

Abstract excerpt

Bone morphogenetic protein (BMP)-4 is an important regulator of cellular growth and differentiation. Expression of BMP-4 has been documented in the gastric mucosa. We reported that incubation of canine parietal cells with EGF for 72 h induced both parietal cell morphological transformation and inhibition of H(+)/K(+)-ATPase gene expression through MAPK-dependent mechanisms. We explored the role of BMP-4 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17600042
DOI: 10.1152/ajpgi.00194.2006

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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