Capacity of UV-irradiated human fibroblasts to support adenovirus DNA synthesis correlates with transcription-coupled repair and is reduced in SV40-transformed cells and cells expressing mutant p53.

doi:10.1111/j.1751-1097.1997.tb03203.x

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Article

Capacity of UV-irradiated human fibroblasts to support adenovirus DNA synthesis correlates with transcription-coupled repair and is reduced in SV40-transformed cells and cells expressing mutant p53.

Photochemistry and photobiology - 1 Nov 1997

McKay B C, Winrow C, Rainbow A J

Abstract excerpt

We have examined the capacity of UV-irradiated human diploid fibroblasts to support adenovirus (Ad) DNA synthesis in order to assess repair of UV-damaged DNA. The capacity of UV-irradiated xeroderma pigmentosum group C (XP-C) fibroblasts to support Ad DNA synthesis was similar to that of UV-irrad...

Topics

Adenoviridae
Cell Line
Cell Transformation, Viral
DNA Repair
DNA, Viral
Fibroblasts
Genes, p53
Humans
Mutation
Simian virus 40
Ultraviolet Rays

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