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Article

The enhanced host-cell permissiveness of human cytomegalovirus is mediated by the Ras signaling pathway.

Biochimica et biophysica acta - 1 Oct 2011

Filippakis Harilaos, Dimitropoulou Panagiota, Eliopoulos Aristides G, Spandidos Demetrios A, Sourvinos George

Abstract excerpt

Human cytomegalovirus utilizes cellular signal transduction pathways to activate viral or cellular transcription factors involved in the control of viral gene expression and DNA replication. In the present study, we demonstrate that Harvey-ras-transformed cells show increased permissiveness to human cytomegalovirus when compared to their parental non-transformed cells. Both the progeny viral yield and the protein...

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Identifiers

PMID: 21782855
DOI: 10.1016/j.bbamcr.2011.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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