Article
Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1996
Burdin N, Galibert L, Garrone P, Durand I, Banchereau J, Rousset F
Abstract excerpt
In response to Ag encounter, B lymphocytes undergo a complex maturation process yielding phenotypically distinct subpopulations that are located in highly organized compartments of secondary lymphoid organs. This study describes the patterns of cytokine secretion of naive, memory, and germinal center (GC) human tonsillar B lymphocytes, activated either through CD40 or B cell receptor or with Staphylococcus aureus...
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