Article
Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1996
Burdin N, Galibert L, Garrone P, Durand I, Banchereau J, Rousset F
Abstract excerpt
In response to Ag encounter, B lymphocytes undergo a complex maturation process yielding phenotypically distinct subpopulations that are located in highly organized compartments of secondary lymphoid organs. This study describes the patterns of cytokine secretion of naive, memory, and germinal ce...
Topics
- Antilymphocyte Serum
- B-Lymphocyte Subsets
- B-Lymphocytes
- Base Sequence
- CD40 Ligand
- Cell Differentiation
- DNA Primers
- Germinal Center
- Humans
- In Vitro Techniques
- Interleukin-6
- Lymphocyte Activation
- Membrane Glycoproteins
- Molecular Sequence Data
- Palatine Tonsil
- Phenotype
- RNA, Messenger
- Receptors, Antigen, B-Cell