Article
CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype.
The Journal of experimental medicine - 1 Jan 1996
Galibert L, Burdin N, de Saint-Vis B, Garrone P, Van Kooten C, Banchereau J, Rousset F
Abstract excerpt
Phenotypic alterations occur when resting human B lymphocytes become germinal center (GC) cells. These include the induction of surface CD38, CD95 (FAS/APO-1), and carboxy-peptidase-M (CPM), a recently described GC marker. However, the factors that govern the in vivo induction of these surface mo...
Topics
- ADP-ribosyl Cyclase
- ADP-ribosyl Cyclase 1
- Antigens, CD
- Antigens, Differentiation
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- CD40 Antigens
- Cell Separation
- Cells, Cultured
- Flow Cytometry
- GPI-Linked Proteins
- Germinal Center
- Humans
- Immunologic Memory