Article
Proliferation and differentiation of human CD5+ and CD5- B cell subsets activated through their antigen receptors or CD40 antigens.
European journal of immunology - 1 Nov 1992
Defrance T, Vanbervliet B, Durand I, Briolay J, Banchereau J
Abstract excerpt
The pan-T cell antigen CD5 has been shown to delineate two different mouse B cell subsets, originating from distinct progenitors. In man, on average, 30% of the tonsillar B cell pool expresses this antigen. In the present report, a detailed comparison of the CD5+ and CD5- B cell response to cytokines, following activation via surface immunoglobulins (sIg) or CD40 antigen, was undertaken. CD5+ B cells were...
Topics
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocyte Subsets
- CD40 Antigens
- CD5 Antigens
- Cell Differentiation
- Cells, Cultured
- Cytokines
- Humans
- Immunoglobulins
- Lymphocyte Activation