Article
Both H-2- and non-H-2-linked genes influence influenza nucleoprotein epitope recognition by CD4+ T cells.
Immunology - 1 Jan 1996
Brett S J, Tite J P
Abstract excerpt
The specificity of the influenza nucleoprotein-induced T-cell proliferative response by mouse strains differing in either H-2- or non-H-2-linked background genes was compared by using a panel of synthetic peptides covering 90% of the nucleoprotein molecule. The results showed, as expected, that H-2 genes strongly influenced the major regions of the molecules recognized by T cells, as the response was focused on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
