Article
Capacity of murine T cells to retain long-term responsiveness to mycobacterial antigens is controlled by the H-2 complex.
Clinical and experimental immunology - 1 Feb 1998
Pichugin A V, Khaidukov S V, Moroz A M, Apt A S
Abstract excerpt
It is firmly established that the allelic composition of the H-2 complex has a prominent impact on the course of tuberculosis (TB) infection in mice, including granuloma formation, mycobacterial spread in the lungs, and the dynamics of mortality. Although intuitively obvious, the role of long-term specific T cell responses in the expression of corresponding phenotypes is poorly understood. In this study we have...
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