Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Obese Gene Expression Alters the Ability of 30A5 Preadipocytes to Respond to Lipogenic Hormones

1 Jun 1996

Abstract excerpt

Leptin, the product of the ob gene, controls food-intake and weight loss in the ob mouse. Although the target(s) of the circulating leptin is presumed to be the brain which then orchestrates food-intake and weight loss, how leptin functions in the process of weight loss is unknown. In this report, we present evidence that ob gene expression in cultured cells suppresses acetyl-CoA carboxylase gene expression and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8663251
DOI: 10.1074/jbc.271.24.13939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Obese Gene Expression Alters the Ability of 30A5 Preadipocytes to Respond to Lipogenic HormonesPMID 8663251Read ↗

Adipose tissue gene expression profiles in ob/ob mice treated with leptinSemantic proximity Read ↗

Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity.Semantic proximity Read ↗

Regulation of energy balance by leptinSemantic proximity Read ↗

Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesitySemantic proximity Read ↗

Selective deletion of leptin receptor in neurons leads to obesity.Semantic proximity Read ↗

[The hormone leptin reduces body weight. A mutant gene makes the mouse obese].Semantic proximity Read ↗

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss.Semantic proximity Read ↗

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.Semantic proximity Read ↗

Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat DietsSemantic proximity Read ↗

Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha.Semantic proximity Read ↗

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.Semantic proximity Read ↗

Mouse Embryonic Fibroblasts Protect ob/ob Mice From Obesity and Metabolic Complications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.