Article
[The hormone leptin reduces body weight. A mutant gene makes the mouse obese].
Lakartidningen - 24 Jan 1996
Meister B, Arvidsson U
Abstract excerpt
The existence of mice (ob/ob mice) with a genetic defect causing obesity and type II diabetes has been known since 1950. The mutated ob gene was recently identified and characterized. The gene encodes a 167 amino acid protein that has been given the name leptin, from the greek word leptos, meanin...
Topics
- Animals
- Arcuate Nucleus of Hypothalamus
- Leptin
- Mice
- Mice, Obese
- Mutation
- Proteins
- Weight Loss
