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Article

New mutations on platelet GPIIb in Sub-Saharan African populations revealed by genotyping discrepancies.

Transfusion - 1 Jul 2008

Hallé L, Jallu V, Mulen-Imandy G, Bigot A, M'bayo K, Anani L Y, Kaplan C

Abstract excerpt

BACKGROUND: Previous studies of platelet allele frequencies in Sub-Saharan African populations enabled us to identify discrepancies in HPA-3 typing, suggesting the presence of new mutations and of a greater polymorphism than so far described in other populations. OBJECTIVES: To analyze these discrepancies and to assess the factors leading to potential alloimmunization in these populations. MATERIALS AND METHODS:...

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PMID: 18422845
DOI: 10.1111/j.1537-2995.2008.01699.x

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