Aberrant methylation of an imprinted gene U2af1-rs1(SP2) caused by its own transgene.

doi:10.1074/jbc.272.14.9120

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Article

Aberrant methylation of an imprinted gene U2af1-rs1(SP2) caused by its own transgene.

The Journal of biological chemistry - 4 Apr 1997

Hatada I, Nabetani A, Arai Y, Ohishi S, Suzuki M, Miyabara S, Nishimune Y, Mukai T

Abstract excerpt

Genomic imprinting refers to the parental allele-specific expression of genes. The precise mechanism underlying this phenomenon, which may involve DNA methylation, is not yet known. U2af1-rs1(SP2) is an imprinted gene expressed from the paternal allele and is methylated on the maternal allele. He...

Topics

Alleles
Animals
DNA Methylation
Female
Genomic Imprinting
Male
Mice
Mice, Inbred C57BL
Nerve Tissue Proteins
Nuclear Proteins
Proteins
Restriction Mapping
Ribonucleoproteins
Spermatozoa
Splicing Factor U2AF
Testis
Transgenes

Source

Open in PubMed

Identifiers

PMID: 9083040
DOI: 10.1074/jbc.272.14.9120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9083040-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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