Clonal hematopoiesis in patients with rheumatoid arthritis

Abstract excerpt

Clonal hematopoiesis (CH) is a phenomenon in which somatic mutations originating from hematopoietic progenitors are detected in peripheral blood cells 1 , 2 . The prevalence of CH increases with age, and CH can be detected in 10–25% of healthy, elderly individuals 1 , 2 , 3 , 4 . Very sensitive methods may allow somatic mutation detection in blood cells in 95% of 50–60-year olds 5 .

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