Article
Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors.
Journal of virology - 1 Feb 1997
Croteau G, Doyon L, Thibeault D, McKercher G, Pilote L, Lamarre D
Abstract excerpt
One hope to maintain the benefits of antiviral therapy against the human immunodeficiency virus type 1 (HIV-1), despite the development of resistance, is the possibility that resistant variants will show decreased viral fitness. To study this possibility, HIV-1 variants showing high-level resista...
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