Mutational analysis of human papillomavirus type 11 E5a oncoprotein.

doi:10.1128/JVI.70.6.3502-3508.1996

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Article

Mutational analysis of human papillomavirus type 11 E5a oncoprotein.

Journal of virology - 1 Jun 1996

Chen S L, Tsai T Z, Han C P, Tsao Y P

Abstract excerpt

In this study, we investigated the structural basis of human papillomavirus type 11 (HPV-11) E5a transforming activity at the amino acid level. The effects of insertion, deletion , and substitution mutations on teh E5a transforming activity were determined by the assay of anchorage-independent gr...

Topics

3T3 Cells
Adenosine Triphosphatases
Amino Acid Sequence
Animals
Base Sequence
Cell Transformation, Neoplastic
Mice
Molecular Sequence Data
Mutation
Oncogene Proteins, Viral
Papillomaviridae
Structure-Activity Relationship
Transfection
Vacuoles

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