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Article

Mutational analysis of human papillomavirus type 11 E5a oncoprotein.

Journal of virology - 1 Jun 1996

Chen S L, Tsai T Z, Han C P, Tsao Y P

Abstract excerpt

In this study, we investigated the structural basis of human papillomavirus type 11 (HPV-11) E5a transforming activity at the amino acid level. The effects of insertion, deletion , and substitution mutations on teh E5a transforming activity were determined by the assay of anchorage-independent growth. In the conserved Cys-X-Cys structure, substitution of Ser for Cys-73 resulted in indistinguishable transforming...

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Identifiers

PMID: 8648683
DOI: 10.1128/JVI.70.6.3502-3508.1996
PMCID: PMC190224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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