Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation.

doi:10.1128/JVI.72.11.8921-8932.1998

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Article

Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation.

Journal of virology - 1 Nov 1998

Klein O, Polack G W, Surti T, Kegler-Ebo D, Smith S O, DiMaio D

Abstract excerpt

The bovine papillomavirus E5 protein is a small, homodimeric transmembrane protein that forms a stable complex with the cellular platelet-derived growth factor (PDGF) beta receptor through transmembrane and juxtamembrane interactions, resulting in receptor activation and cell transformation. Glut...

Topics

Animals
Bovine papillomavirus 1
COS Cells
Cattle
Cell Line
Cell Transformation, Viral
Dimerization
Genes, Viral
Glutamine
Models, Molecular
Mutation
Oncogene Proteins, Viral
Protein Conformation
Receptor, Platelet-Derived Growth Factor beta
Receptors, Platelet-Derived Growth Factor

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Identifiers

PMID: 9765437
DOI: 10.1128/JVI.72.11.8921-8932.1998
PMCID: PMC110309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9765437-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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