Article
Oligomerization of the E5 protein of human papillomavirus type 16 occurs through multiple hydrophobic regions.
Virology - 1 Sept 2003
Gieswein Christine E, Sharom Frances J, Wildeman Alan G
Abstract excerpt
The high risk forms of human papillomavirus (HPV) (primarily types 16 and 18) are the leading cause of cervical cancer worldwide. Infection results in expression of three oncoproteins, E5, E6, and E7, the latter two being of predominant importance in maintaining a transformed state of the host epithelial cell. While little is known about the role(s) of the HPV E5, the bovine papillomavirus type 1 (BPV1) E5...
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