Article
Accelerated evolution in inhibitor domains of porcine elafin family members.
The Journal of biological chemistry - 22 Mar 1996
Tamechika I, Itakura M, Saruta Y, Furukawa M, Kato A, Tachibana S, Hirose S
Abstract excerpt
Through the analysis of the porcine gene encoding the elastase inhibitor elafin, we demonstrated that there are at least three closely related members of the elafin family, and their genes have arisen by accelerated evolution. A porcine genomic DNA library was screened with a previously cloned hu...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Cloning, Molecular
- DNA
- Exons
- Humans
- Introns
- Molecular Sequence Data
- Mutation
- Proteinase Inhibitory Proteins, Secretory
- Proteins
- Repetitive Sequences, Nucleic Acid
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Serine Proteinase Inhibitors
- Swine