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Article

Accelerated evolution in inhibitor domains of porcine elafin family members.

The Journal of biological chemistry - 22 Mar 1996

Tamechika I, Itakura M, Saruta Y, Furukawa M, Kato A, Tachibana S, Hirose S

Abstract excerpt

Through the analysis of the porcine gene encoding the elastase inhibitor elafin, we demonstrated that there are at least three closely related members of the elafin family, and their genes have arisen by accelerated evolution. A porcine genomic DNA library was screened with a previously cloned human elafin cDNA probe, and several positive clones were obtained that can be distinguished by a combination of...

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PMID: 8636131
DOI: 10.1074/jbc.271.12.7012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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