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Article

Adaptive evolution and functional divergence of pepsin gene family.

Gene - 26 May 2004

Carginale Vincenzo, Trinchella Francesca, Capasso Clemente, Scudiero Rosaria, Riggio Marilisa, Parisi Elio

Abstract excerpt

In vertebrates, a large proportion of genes is organized in gene families. Paralogous gene groups generated by gene duplication are related by homology, high degree of sequence identity and similar structural architecture of their products. Aspartic proteinases form a widely distributed protein superfamily including cathepsins, pepsins, renin and napsin. In the present study, the nucleotide sequences coding for...

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Identifiers

PMID: 15177683
DOI: 10.1016/j.gene.2004.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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