Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virusX gene

1 Apr 1996

Abstract excerpt

The role of the hepatitis B virus (HBV) X protein in liver tumorigenesis is unresolved. Transgenic mice harboring the X gene (nt 1376-1840 under the control of the human alpha-1-antitrypsin regulatory elements) (ATX mice) display only minor histopathologic alterations of the liver. To determine if ATX mice are more susceptible to the effects of hepatocarcinogens, 12- to 15-d-old male ATX and control littermate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to Hepatitis B Virus Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8634084
DOI: 10.1002/(sici)1098-2744(199604)15:4<261::aid-mc3>3.0.co;2-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virusX genePMID 8634084Read ↗

Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis.Semantic proximity Read ↗

Expression of Hepatitis B Virus X Protein Does Not Alter the Accumulation of Spontaneous Mutations in Transgenic MiceSemantic proximity Read ↗

Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein.Semantic proximity Read ↗

Hepatitis B virus transactivator X protein is not tumorigenic in transgenic miceSemantic proximity Read ↗

Contribution of C1485T mutation in the HBx gene to human and murine hepatocarcinogenesis.Semantic proximity Read ↗

Compensatory apoptosis in preneoplastic liver of a transgenic mouse model for viral hepatocarcinogenesis.Semantic proximity Read ↗

Constitutive Androstane Receptor and Hepatitis B Virus X Protein Cooperatively Induce β-catenin-Activated Liver TumorsSemantic proximity Read ↗

Rapid development of hepatic tumors in transforming growth factor α transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by <i>N</i>-nitrosodiethylamine and promoted by phenobarbitalSemantic proximity Read ↗

Enhancement of hepatitis B virus replication by its X protein in transgenic mice.Semantic proximity Read ↗

Modeling Hepatitis B Virus X–Induced Hepatocellular Carcinoma in Mice With the Sleeping Beauty Transposon System ΔSemantic proximity Read ↗

Hepatitis B injury, male gender, aflatoxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice.Semantic proximity Read ↗

Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.