Article
An apparently dominant bipolar affective disorder (BPAD) locus on chromosome 20p11.2-q11.2 in a large Turkish pedigree.
European journal of human genetics : EJHG - 1 Jan 2001
Radhakrishna U, Senol S, Herken H, Gucuyener K, Gehrig C, Blouin J L, Akarsu N A, Antonarakis S E
Abstract excerpt
Bipolar affective disorder (BPAD), also known as manic-depressive illness, is a common complex, polygenic disorder characterised by recurrent cyclic episodes of mania and depression. Family, twin, and adoption studies strongly suggest a genetic predisposition/susceptibility to BPAD, but no genes have yet been identified. We studied a large Turkish pedigree, with an apparently autosomal dominant BPAD, which...
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