Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae.

Current genetics - 1 Apr 1996

Grey M, Schmidt M, Brendel M

Abstract excerpt

In an attempt to clone genes involved in resistance to formaldehyde we have screened a genomic library based on the episomal plasmid YEp24 for the ability to increase resistance to formaldehyde in a wild-type strain. In addition to SFA, the gene encoding the formaldehyde dehydrogenase Adh5, an en...

Topics

1-Propanol
Alcohol Dehydrogenase
Cloning, Molecular
Drug Resistance, Microbial
Formaldehyde
Genes, Fungal
Phenotype
Propanols
Saccharomyces cerevisiae
Substrate Specificity

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8625422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8625422-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae.PMID 8625422Read ↗

A mutated ARO4 gene for feedback-resistant DAHP synthase which causes both o-fluoro-DL-phenylalanine resistance and beta-phenethyl-alcohol overproduction in Saccharomyces cerevisiae.Semantic proximity Read ↗

Glutathione, but not transcription factor Yap1, is required for carbon source-dependent resistance to oxidative stress in Saccharomyces cerevisiae.Semantic proximity Read ↗

Pathways for transcriptional activation of a glutathione-dependent formaldehyde dehydrogenase gene.Semantic proximity Read ↗

Low ergosterol content in yeast adh1 mutant enhances chitin maldistribution and sensitivity to paraquat-induced oxidative stress.Semantic proximity Read ↗

A strong nitrogen source-regulated promoter for controlled expression of foreign genes in the yeast Pichia pastoris.Semantic proximity Read ↗

The Pichia pastoris formaldehyde dehydrogenase gene (FLD1) as a marker for selection of multicopy expression strains of P. pastoris.Semantic proximity Read ↗

Effect of irradiation and mutagenic chemicals on the generation of ADH2- and ADH4-constitutive mutants in yeast: the inducibility of Ty transposition by UV and ethyl methanesulfonate.Semantic proximity Read ↗

Positive selection of novel peroxisome biogenesis-defective mutants of the yeast Pichia pastoris.Semantic proximity Read ↗

Overexpression of peroxisomal malate dehydrogenase MDH3 gene enhances cell death on H2O2 stress in the ald5 mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Cloning of the Arabidopsis and Rice Formaldehyde Dehydrogenase Genes: Implications for the Origin of Plant ADH EnzymesSemantic proximity Read ↗

Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenaseSemantic proximity Read ↗

Novel formaldehyde-activating enzyme in Methylobacterium extorquens AM1 required for growth on methanol.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.