Pathways for transcriptional activation of a glutathione-dependent formaldehyde dehydrogenase gene.

doi:10.1006/jmbi.1998.1900

Back to search

Article

Pathways for transcriptional activation of a glutathione-dependent formaldehyde dehydrogenase gene.

Journal of molecular biology - 31 Jul 1998

Barber R D, Donohue T J

Abstract excerpt

The widespread occurrence of glutathione-dependent formaldehyde dehydrogenases (GSH-FDH) suggests that this enzyme serves a conserved function in preventing the cytogenetic and potentially lethal interaction of formaldehyde with nucleic acids, proteins and other cell constituents. Despite this po...

Topics

Aldehyde Oxidoreductases
Alleles
DNA Methylation
Formaldehyde
Gene Expression Regulation, Bacterial
Genes, Bacterial
Glutathione
Promoter Regions, Genetic
Rhodobacter sphaeroides
Transcriptional Activation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.