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Article

Novel formaldehyde-activating enzyme in Methylobacterium extorquens AM1 required for growth on methanol.

Journal of bacteriology - 1 Dec 2000

Vorholt J A, Marx C J, Lidstrom M E, Thauer R K

Abstract excerpt

Formaldehyde is toxic for all organisms from bacteria to humans due to its reactivity with biological macromolecules. Organisms that grow aerobically on single-carbon compounds such as methanol and methane face a special challenge in this regard because formaldehyde is a central metabolic intermediate during methylotrophic growth. In the alpha-proteobacterium Methylobacterium extorquens AM1, we found a previously...

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Identifiers

PMID: 11073907
DOI: 10.1128/JB.182.23.6645-6650.2000
PMCID: PMC111405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel formaldehyde-activating enzyme in Methylobacterium extorquens AM1 required for growth on methanol.PMID 11073907Read ↗

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Genetic and phenotypic comparison of facultative methylotrophy between Methylobacterium extorquens strains PA1 and AM1.Semantic proximity Read ↗

EfgA is a conserved formaldehyde sensor that halts bacterial translation in response to elevated formaldehydeSemantic proximity Read ↗

Pyrroloquinoline Quinone Ethanol Dehydrogenase in Methylobacterium extorquens AM1 Extends Lanthanide-Dependent Metabolism to Multicarbon Substrates.Semantic proximity Read ↗

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Development of an insertional expression vector system for Methylobacterium extorquens AM1 and generation of null mutants lacking mtdA and/or fch.Semantic proximity Read ↗

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