Activation of signalling by the activin receptor complex.

doi:10.1128/MCB.16.3.1066

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Article

Activation of signalling by the activin receptor complex.

Molecular and cellular biology - 1 Mar 1996

Attisano L, Wrana J L, Montalvo E, Massagué J

Abstract excerpt

Activin exerts its effects by simultaneously binding to two types of p rotein serine/threonine kinase receptors, each type existing in various isoforms. Using the ActR-IB and ActR-IIB receptor isoforms, we have investigated the mechanism of activin receptor activation. ActR-IIB are phosphoprotein...

Topics

Activin Receptors
Amino Acid Sequence
Animals
Cell Line
Ligands
Molecular Sequence Data
Mutation
Protein Serine-Threonine Kinases
Receptors, Growth Factor
Signal Transduction
Transfection

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