Article
Regulation of activin type I receptor function by phosphorylation of residues outside the GS domain.
FEBS letters - 29 Dec 1997
Willis S A, Mathews L S
Abstract excerpt
Activin signals through a heteromeric complex of receptor serine kinases by inducing type II receptor-mediated phosphorylation, and consequent activation, of the type I receptor. Type I receptor phosphorylation occurs at a glycine- and serine-rich site in the juxtamembrane domain; phosphorylation at that site correlates with signaling. Investigation of type I activin receptor mutants impaired for GS domain...
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