Article
Detection of CYP3A5 allelic variant: a candidate for the polymorphic expression of the protein?
Biochemical and biophysical research communications - 16 Apr 1996
Jounaïdi Y, Hyrailles V, Gervot L, Maurel P
Abstract excerpt
In liver samples from 19 Caucasian subjects, the CYP3A5 protein was detected in 74% of individuals (14/19), while the messenger was shown to be expressed in 100% of individuals, assessed by the RT-PCR method. In order to characterise the putative mutation(s) in the messenger, accounting for the absence of protein accumulation, the full coding region of the CYP3A5 cDNA was sequenced for two unrelated individuals,...
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