Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phospholipase D signaling is essential for meiosis.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 1995

Rose K, Rudge S A, Frohman M A, Morris A J, Engebrecht J

Abstract excerpt

Phospholipid metabolism plays an important role in cellular regulation by generating second messengers for signal transduction. Many stimuli activate a phospholipase D, which catalyzes the hydrolysis of phosphatidylcholine, producing phosphatidic acid and choline. Here we report that the yeast SP014 gene, which is essential for meiosis [Honigberg, S. M., Conicella, C. & Esposito, R. E. (1992) Genetics 130,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Recombinant Proteins

Share to Saccharomyces cerevisiae

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 8618862
DOI: 10.1073/pnas.92.26.12151
PMCID: PMC40314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phospholipase D signaling is essential for meiosis.PMID 8618862Read ↗

SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes.Semantic proximity Read ↗

Phosphatidylinositol biosynthesis: biochemistry and regulation.Semantic proximity Read ↗

Relocalization of phospholipase D activity mediates membrane formation during meiosis.Semantic proximity Read ↗

Identification of a novel, Ca(2+)-dependent phospholipase D with preference for phosphatidylserine and phosphatidylethanolamine in Saccharomyces cerevisiae.Semantic proximity Read ↗

The role and relevance of phospholipase D1 during growth and dimorphism of Candida albicans.Semantic proximity Read ↗

Identification of yeast meiosis-specific genes by differential display.Semantic proximity Read ↗

Disruption of a gene encoding phosphatidic acid phosphatase causes abnormal phenotypes in cell growth and abnormal cytokinesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Srf1 is a novel regulator of phospholipase D activity and is essential to buffer the toxic effects of C16:0 platelet activating factor.Semantic proximity Read ↗

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects.Semantic proximity Read ↗

Differential requirement for phospholipase D/Spo14 and its novel interactor Sma1 for regulation of exocytotic vesicle fusion in yeast meiosis.Semantic proximity Read ↗

Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.