Article
Relocalization of phospholipase D activity mediates membrane formation during meiosis.
The Journal of cell biology - 12 Jan 1998
Rudge S A, Morris A J, Engebrecht J
Abstract excerpt
Phospholipase D (PLD) enzymes catalyze the hydrolysis of phosphatidylcholine and are involved in membrane trafficking and cytoskeletal reorganization. The Saccharomyces cerevisiae SPO14 gene encodes a PLD that is essential for meiosis. We have analyzed the role of PLD in meiosis by examining two mutant proteins, one with a point mutation in a conserved residue (Spo14pK--> H) and one with an amino-terminal...
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