Article
Disruption of a gene encoding phosphatidic acid phosphatase causes abnormal phenotypes in cell growth and abnormal cytokinesis in Saccharomyces cerevisiae.
Biochemical and biophysical research communications - 9 Jul 1998
Katagiri T, Shinozaki K
Abstract excerpt
Phosphatidic acid phosphatase (PAP) is an enzyme involved in lipid metabolism. Diacylglycerol (DG) and phosphatidic acid (PA) are a substrate and a product of PAP, respectively, and function as second messengers in several signal transduction pathways in animals. To investigate the function of PA...
Topics
- Amino Acid Sequence
- Cell Division
- Cloning, Molecular
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Phenotype
- Phosphatidate Phosphatase
- Recombinant Proteins
- Saccharomyces cerevisiae
- Transformation, Genetic