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Article

Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila.

Open biology - 1 Jan 2016

Laurinyecz Barbara, Péter Mária, Vedelek Viktor, Kovács Attila L, Juhász Gábor, Maróy Péter, Vígh László, Balogh Gábor, Sinka Rita

Abstract excerpt

Drosophila spermatogenesis is an ideal system to study the effects of changes in lipid composition, because spermatid elongation and individualization requires extensive membrane biosynthesis and remodelling. The bulk of transcriptional activity is completed with the entry of cysts into meiotic division, which makes post-meiotic stages of spermatogenesis very sensitive to even a small reduction in gene products....

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Source

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Identifiers

PMID: 26791243
DOI: 10.1098/rsob.150169
PMCID: PMC4736822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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