Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects.

doi:10.1073/pnas.95.21.12346

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Article

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects.

Proceedings of the National Academy of Sciences of the United States of America - 13 Oct 1998

Xie Z, Fang M, Rivas M P, Faulkner A J, Sternweis P C, Engebrecht J A, Bankaitis V A

Abstract excerpt

Yeast phosphatidylinositol transfer protein (Sec14p) function is essential for production of Golgi-derived secretory vesicles, and this requirement is bypassed by mutations in at least seven genes. Analyses of such 'bypass Sec14p' mutants suggest that Sec14p acts to maintain an essential Golgi me...

Topics

Carrier Proteins
Catalysis
Ethanol
Membrane Proteins
Mutation
Phenotype
Phosphatidylcholines
Phospholipase D
Phospholipid Transfer Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 9770489
DOI: 10.1073/pnas.95.21.12346
PMCID: PMC22834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9770489-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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