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Article

Heterogeneous mutation of the RET proto-oncogene in subpopulations of medullary thyroid carcinoma.

Cancer research - 1 May 1996

Eng C, Mulligan L M, Healey C S, Houghton C, Frilling A, Raue F, Thomas G A, Ponder B A

Abstract excerpt

Mutations in the RET proto-oncogene are associated with the pathogenesis of medullary thyroid carcinoma (MTC). In an attempt to understand this process, we examined microdissected subpopulations from MTC and multiple metastases from these tumors. Approximately 80% of sporadic MTC's had at least o...

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Source

Identifiers

PMID: 8616867

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8616867-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Heterogeneous mutation of the RET proto-oncogene in subpopulations of medullary thyroid carcinoma.PMID 8616867Read ↗

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Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas.Semantic proximity Read ↗

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