Article
A case of metastatic medullary thyroid carcinoma: early identification before surgery of an RET proto-oncogene somatic mutation in fine-needle aspirate specimens.
The Journal of clinical endocrinology and metabolism - 1 Oct 1997
Russo D, Arturi F, Chiefari E, Meringolo D, Bianchi D, Bellanova B, Filetti S
Abstract excerpt
Medullary thyroid carcinoma (MTC) management requires determination of the sporadic or familial nature of the disease. RET proto-oncogene mutation analysis in the tumor tissue obtained at surgery and in the peripheral blood identifies somatic vs. germinal mutations. We now report a case of MTC in...
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