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Article

Low Prevalence of the Somatic M918T <i>RET</i> Mutation in Micro-Medullary Thyroid Cancer

9 Mar 2012

Abstract excerpt

BACKGROUND: The prevalence of RET somatic mutations in sporadic medullary thyroid cancer (MTCs) is ∼40%-50%, and the most frequent somatic mutation is M918T. RET-positive MTCs have been demonstrated to have a more advanced stage at diagnosis and a worse outcome. AIMS: The aim of the present work was to compare the prevalence of RET somatic mutations in sporadic microMTCs (<1 cm) and in larger MTCs. PATIENTS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22404432
DOI: 10.1089/thy.2011.0358

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