Article
Polymorphism at the glutathione S-transferase locus GSTM3: interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma.
Cancer research - 1 May 1996
Yengi L, Inskip A, Gilford J, Alldersea J, Bailey L, Smith A, Lear J T, Heagerty A H, Bowers B, Hand P, Hayes J D, Jones P W, Strange R C, Fryer A A
Abstract excerpt
The influence of polymorphism in the glutathione S-transferase, GSTM3 gene on susceptibility to cutaneous basal cell carcinoma (BCC) has been investigated. We have reported previously two GSTM3 alleles, GSTM3*A and GSTM3*B, distinguished by a recognition motif for the YY1 transcription factor in...
Topics
- Aged
- Alleles
- Carcinoma, Basal Cell
- Cytochrome P-450 Enzyme System
- Female
- Genotype
- Glutathione Transferase
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Neoplasms, Multiple Primary
- Polymorphism, Genetic