Article
Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours.
Pharmacogenetics - 1 Aug 2000
Ramachandran S, Hoban P R, Ichii-Jones F, Pleasants L, Ali-Osman F, Lear J T, Smith A G, Bowers B, Jones P W, Fryer A A, Strange R C
Abstract excerpt
We previously described associations between basal cell carcinoma (BCC) numbers and allelic variants at loci that mediate host response to ultraviolet radiation (UV). These associations were largely exerted in cases with the multiple presentation phenotype (MPP). This phenotype describes patients who present at their first or a later presentation with a cluster of BCC (2-10 new BCC). Remaining BCC cases have the...
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