Article
A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 1995
Zellmer E, Zhang Z, Greco D, Rhodes J, Cassel S, Lewis E J
Abstract excerpt
In order to characterize the specificity of expression of the neurotransmitter biosynthetic gene dopamine beta-hydroxylase (DBH), the identification of proteins that interact with the DB1 enhancer was initiated. A homeobox-containing cDNA was isolated from a PC12 expression cDNA library screened...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Dopamine beta-Hydroxylase
- Genes
- Genes, Homeobox
- Homeodomain Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Norepinephrine
- Oligonucleotide Probes
- Promoter Regions, Genetic
- RNA, Messenger