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Article

Specification of the central noradrenergic phenotype by the homeobox gene Phox2b.

Molecular and cellular neurosciences - 1 Mar 2000

Pattyn A, Goridis C, Brunet J F

Abstract excerpt

The closely related homeobox genes Phox2a and Phox2b are expressed in all central and peripheral noradrenergic neurons. Our previous results have shown that Phox2a controls the differentiation of the main noradrenergic center of the brain, the locus coeruleus, but leaves unaffected the other noradrenergic centers. Here, we report that Phox2b has a wider and overlapping role, in that it is required for the...

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Identifiers

PMID: 10736201
DOI: 10.1006/mcne.1999.0826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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