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Article

The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 2004

Bassett Mary H, Suzuki Takashi, Sasano Hironobu, White Perrin C, Rainey William E

Abstract excerpt

Aldosterone biosynthesis in the zona glomerulosa of the adrenal cortex is regulated by transcription of CYP11B2 (encoding aldosterone synthase). The effects of nerve growth factor-induced clone B (NGFIB) (NR4A1), Nur-related factor 1 (NURR1) (NR4A2), and steroidogenic factor-1 (SF-1) (NR5A1) on transcription of human CYP11B2 (hCYP11B2) and hCYP11B1 (11 beta-hydroxylase) were compared in human H295R adrenocortical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14645496
DOI: 10.1210/me.2003-0005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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