Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathway.

doi:10.1006/dbio.1995.8033

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Article

Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathway.

Developmental biology - 1 Dec 1995

Bang A G, Bailey A M, Posakony J W

Abstract excerpt

In Drosophila imaginal discs, the function of the Hairless (H) gene is required at multiple steps during the development of adult sensory organs. Here we report the results of a series of experiments designed to investigate the in vivo role of H in sensory organ precursor (SOP) cell specification...

Topics

Animals
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Membrane Proteins
Mutation
Promoter Regions, Genetic
Proteins
Receptors, Notch
Signal Transduction
Transcription Factors

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