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Article

A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.

Development (Cambridge, England) - 1 May 2003

Koelzer Stefan, Klein Thomas

Abstract excerpt

Su(H)/CBF1 is a key component of the evolutionary conserved Notch signalling pathway. It is a transcription factor that acts as a repressor in the absence of the Notch signal. If Notch signalling is activated, it associates with the released intracellular domain of the Notch receptor and acts as an activator of transcription. During the development of the mechanosensory bristles of Drosophila, a selection process...

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Identifiers

PMID: 12642500
DOI: 10.1242/dev.00426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.PMID 12642500Read ↗

Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathway.Semantic proximity Read ↗

Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila.Semantic proximity Read ↗

Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless.Semantic proximity Read ↗

Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development.Semantic proximity Read ↗

Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless.Semantic proximity Read ↗

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.Semantic proximity Read ↗

Opposing inputs by Hedgehog and Brinker define a stripe of hairy expression in the Drosophila leg imaginal disc.Semantic proximity Read ↗

senseless is necessary for the survival of embryonic salivary glands in Drosophila.Semantic proximity Read ↗

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Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless.Semantic proximity Read ↗

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Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila.Semantic proximity Read ↗

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