Article
The relationship between smoking exposure and p53 overexpression in colorectal cancer.
British journal of cancer - 1 Apr 1996
Freedman A N, Michalek A M, Marshall J R, Mettlin C J, Petrelli N J, Zhang Z F, Black J D, Satchidanand S, Asirwatham J E
Abstract excerpt
Although epidemiological studies of the relationship between cigarette smoking and colorectal cancer risk have been equivocal, a positive association is consistently found for colorectal adenoma development. We performed an epidemiological study to determine whether p53 protein overexpression, in tumours obtained at the time of resection, is associated with cigarette exposure in colorectal cancer. A total of 163...
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