Article
Gene-smoking interaction on colorectal adenoma and cancer risk: review and meta-analysis.
Mutation research - 2 Nov 2009
Raimondi Sara, Botteri Edoardo, Iodice Simona, Lowenfels Albert B, Maisonneuve Patrick
Abstract excerpt
The etiology of colorectal cancer is complex and multifactorial. Tobacco smoke has been found to be associated both with colorectal adenoma and cancer development. It was hypothesized that tobacco smoking could interact with genetic factors, providing different risk estimates according to different genetic predisposition. We reviewed and summarized by a meta-analytic approach the evidence from the literature on...
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