Article
cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells.
Archives of biochemistry and biophysics - 15 Feb 1996
Biagini C, Celier C
Abstract excerpt
Cytochromes P450 (CYP) are ubiquitous enzymes which metabolize multiple endogenous and exogenous substrates. CYP2C11 is the most abundant among the P450s present in untreated rat liver (approximately 50% of total P450) and is known for metabolizing testosterone mainly in positions 2 alpha and 16...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Aryl Hydrocarbon Hydroxylases
- Base Sequence
- Cell Line
- Chlorocebus aethiops
- Cloning, Molecular
- Cytochrome P-450 Enzyme System
- Cytochrome P450 Family 2
- DNA, Complementary
- Gene Expression
- Genetic Variation
- In Vitro Techniques
- Male
- Molecular Sequence Data
- Oligonucleotide Probes
- Point Mutation