Article
Molecular basis of left-right asymmetry.
Development, growth & differentiation - 1 Dec 1999
Tamura K, Yonei-Tamura S, Izpisúa Belmonte J C
Abstract excerpt
In vertebrates visceral asymmetry is conserved along the left-right axis within the body. Only a small percentage of randomization (situs ambiguus), or complete reversal (situs inversus) of normal internal organ position and structural asymmetry is found in humans. A breakdown in left-right asymmetry is occasionally associated with severe malformations of the organs, clearly indicating that the regulated...
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