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DNA repair and epidemiology of basal cell carcinoma

1 Dec 1995

Abstract excerpt

In a molecular epidemiological study of DNA repair, host reactivation assay was used to measure the DNA repair capacity of cryopreserved lymphocytes from 88 primary basal cell carcinoma (BCC) patients and 135 cancer-free controls. In this study population, reduced repair of ultraviolet radiation-induced DNA damage contributed to the risk of sunlight-induced BCC. A family history of BCC is associated with low DNA...

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PMID: 7497645
DOI: 10.1093/clinchem/41.12.1854

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