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Article

Two-stage model of radon-induced malignant lung tumors in rats: effects of cell killing.

Radiation research - 1 Feb 1996

Luebeck E G, Curtis S B, Cross F T, Moolgavkar S H

Abstract excerpt

A two-stage stochastic model of carcinogenesis is used to analyze lung tumor incidence in 3750 rats exposed to varying regimens of radon carried on a constant-concentration uranium ore dust aerosol. New to this analysis is the parameterization of the model such that cell killing by the alpha particles could be included. The model contains parameters characterizing the rate of the first mutation, the net...

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PMID: 8606926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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