Article
Two-stage model of radon-induced malignant lung tumors in rats: effects of cell killing.
Radiation research - 1 Feb 1996
Luebeck E G, Curtis S B, Cross F T, Moolgavkar S H
Abstract excerpt
A two-stage stochastic model of carcinogenesis is used to analyze lung tumor incidence in 3750 rats exposed to varying regimens of radon carried on a constant-concentration uranium ore dust aerosol. New to this analysis is the parameterization of the model such that cell killing by the alpha part...
Topics
- Animals
- Cell Division
- Clone Cells
- Dose-Response Relationship, Radiation
- Likelihood Functions
- Lung Neoplasms
- Male
- Models, Biological
- Mutation
- Neoplasms, Radiation-Induced
- Radon
- Rats
- Rats, Wistar