A rapid-mutation approximation for cell population dynamics.

Abstract excerpt

Carcinogenesis and cancer progression are often modeled using population dynamics equations for a diverse somatic cell population undergoing mutations or other alterations that alter the fitness of a cell and its progeny. Usually it is then assumed, paralleling standard mathematical approaches to evolution, that such alterations are slow compared to selection, i.e., compared to subpopulation frequency changes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Aneuploidy
• Share to Cell Communication