A generalized Luria-Delbrück model.

doi:10.1016/j.mbs.2005.07.003

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Article

A generalized Luria-Delbrück model.

Mathematical biosciences - 1 Oct 2005

Dewanji A, Luebeck E G, Moolgavkar S H

Abstract excerpt

We develop extensions of the Luria-Delbrück model that explicitly consider non-exponential growth of normal cells and a birth-death process with mean exponential or Gompertz growth of mutants. Death of mutant cells can be important in clones arising during cancer progression. The use of a birth-death process for growth of mutant cells, as opposed to a pure birth process as in previous work on the Luria-Delbrück...

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PMID: 16137718
DOI: 10.1016/j.mbs.2005.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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